Administer by deep IM injection into large mass muscle.
Intramuscular doses over 1 g divided between more than onesite.
Do not administer the intramuscular formulation intravenously because it contains lidocainne.
Check injection site for induration, sterile abscess and tissue sloughing; change site every 3 days.
Administer by slow IV injection (over at least 2-4 minutes) or by intermittent IV infusion (over 30 mins).
Give IV after diluting in NS, D5W, or sterile H20 for injection.
Intravenous doses greater than or equal to 50 mg/kg body- weight in infants and children up to 12 years of age should be given by slow infusion over at least 30 minutes.
In neonates, administer intravenous doses over 60 minutes to reduce the potential risk of biliubin encephalopathy (see also under Contra-indications).
Do not admix with aminoglycosides in same bottle/bag.
Avoid use with calcium-containing diluents or infusions for intravenous use e.g., Ringer’s solution (may cause the formation of a ceftriaxone-calcium precipitate)
Reconstitution and Administration:
According to manufacturer’s directions.
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